|Voiced by|| Wayne Knight|
|First appearance||Hercules (TV series) (1998-1999)|
|Last appearance||Hercules (TV series) (1998-1999)|
|Orthrus as a baby.|
Orthos first appears when he is visited Echidna, who puts them on a strict hero diet as opposed to their days of eating delivery boys. When Hercules arrives on the scene to fight Orthos, they have an easy time defeating him and see him as a nobody. But when discovering Hercules' Student ID and that Prometheus Academy has a lot of choice meals, they target the school. Hercules manages to defeat Orthos, though Adonis and his soldiers end up taking the credit.
Frustrated with the humiliation they received after being defeated by Hercules from the monster community, Orthos plans a revenge scheme and figures he can track Hercules down to the Pita Pit.
- In the original Greek myth Orthos was a two-headed dog rather than a two-headed cyclops.
- As an infant Orthos had an apparently rough relationship with the Minotaur after the latter threw a block at his eye.